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Coagulation disorders, including von Willebrand disease and platelet dysfunction, may present with menorrhagia or intermenstrual bleeding
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Experimental doses in animal studies: 0.025 to 0.1 mg/kg subcutaneously , often with a loading phase (daily for 1 week) and maintenance phase (twice weekly)
Inflammatory bowel disease, previous gastric surgery, or other structural gastrointestinal abnormalities may also influence treatment response
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