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As of early 2026, the longest documented use of Retatrutide in a controlled clinical setting is 68 weeks
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Pregnancy and nursing: No safety data exists
This was maintained until the end of the 12-month follow-up period. During that time, the patients mean HbA1c fell to 5.9 at six months and 5.7 at 12 months
Cardiovascular protection and kidney benefits Both medications are proven to reduce the risk of Major Adverse Cardiovascular Events (MACE), such as heart attack, stroke, and death due to cardiovascular disease in patients with type 2 diabetes and established heart and blood vessels related diseases
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