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Appleton highlighted several important remaining gaps in the understanding of GLP-1-based therapies for OA

Her expertise in medical and cosmetic dermatology has won her a legion of beloved patients, respect from colleagues nationwide and accolades including Top Doctor in Connecticut and Top 25 Most Influential People of Litchfield County

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Given that this dose is similar to the baseline insulin dose (54 IU/day) in PIONEER 8, the same dose was applied to the metformin + oral semaglutide 14 mg + insulin glargine combination

For optimal results, Glutathione 10%/Ascorbic Acid 5% Topical Cream should be applied to the affected area twice daily, or as directed by your healthcare provider