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N Engl J Med 2006

If you're more than 3 days late, dose as soon as you remember (regardless of meal timing) to restore plasma levels, then resume your normal schedule the following week

TB-500 TB-500 represents a synthetic analogue of thymosin beta-4, a naturally occurring 43-amino acid polypeptide that is highly conserved across species and found in elevated concentrations in platelets, macrophages, and wound healing tissues

The 2008 Lancet trial that established tesofensine's efficacy also documented cardiovascular adverse events in 18% of participants at the 1mg dose