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Injectable healing protocol: 23 mg daily (upper end of range), systemic injection - not into the wound itself - daily until the wound resolves, plus 12 weeks maintenance Topical healing protocol: 2 %4 % in a wound-appropriate vehicle applied 23 times daily to wound margins (never into an open, actively bleeding wound) under clinician supervision Stacking: GHK-Cu pairs exceptionally well with BPC-157 and TB-500 - the so-called GLOW stack - for complex healing cases

The use of NNMT inhibitors as a potential obesity treatment has been investigated preclinically 8,9,13 , and observational clinical data suggests that increased NNMT expression and activity correlate with increased incidence of Type 2 diabetes (T2D) and risk of obesity, respectively 10,11

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Moreover, the simulations confirmed that the Cagri P37 had weaker interactions with the ECDs leading to greater uncoupling of the peptide C-terminus from the ECDs (Supplementary Movie 1, Supplementary Tables 4, 5), and parallel increases in the dynamics of the peptide as it engaged with the CTR TM bundle, including F23