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Los estudios indican que los efectos gastrointestinales son la causa ms comn de discontinuacin del tratamiento con GLP-1, lo que subraya la importancia de estrategias efectivas de manejo

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Conversely, inhibiting TLR4 can suppress microglial activation, alleviate neuroinflammation, improve cognitive function, and mitigate synaptic plasticity impairments and depression-like symptoms via this pathway (159, 160)