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In exploring the treatment of obesity and its associated complications, such as Type 2 diabetes and cardiovascular disease, a prominent and popular target is the Glucagon-Like Peptide-1 Receptor (GLP-1R)

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Ligand binding assays Direct ligand binding experiments were performed using the HTRF signal between GHSR labeled at its N-terminus with Lumi-4 Tb and a ghrelin peptide labeled with dy647 on an additional cysteine positioned at its C-terminus 33

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