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The susceptibility of ferroptosis is modulated by diverse biological mechanisms, including p53 deficiency (Tarangelo et al., 2018), DNA damage signaling pathways ( 3.1 Therapies targeting ferroptosis-related signaling pathways and genes Ferroptosis has emerged as a promising therapeutic avenue for various treatment-resistant cancers, as evidenced by recent literature (Ratner et al., 2010)
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