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Domain-mapping assays indicated that UFL1 associates with AKT1 via its N-terminus (Fig

GSH is exclusively degraded at the extracellular level by cells expressing -glutamyltranspeptidase (GGT), such as those of the hepatobiliary tree and of other organs like the heart, kidney, lungs, pancreas, and seminal vesicles

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However, the lower bioavailability may require higher doses or longer treatment periods to achieve comparable results, if achievable at all