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The Human Gene Mutation Database (HGMD) contains 43 different GSS variants that have been reported as of January 2023, with missense variants showing predominance (55.8%), followed by splice variants (21.0%), small insertions/deletions (11.5%), large insertions/deletions (7.0%), and nonsense variants (4.7%)

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Additional published context on Bioma's synbiotic formulation approach is available through a 2025 prebiotic, probiotic, and postbiotic synergy overview and an earlier consumer informational piece on probiotic supplement category developments

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