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Preparation of vitrified specimen EM grids (Quantifoil, Grolbichau, Germany, 200 mesh copper R1.2/1.3) were glow discharged for 30 s in high-pressure air using Harrick plasma cleaner (Harrick, Ithaca, NY)

Mater 12 (11), 9911003

Metformin treatment has previously been explored clinically in CRC, but contradictory findings have been reported 81,82,83

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