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Furthermore, intravenous administration of high-dose selenium enhances the effects of selenium with acceptable toxicity, with adverse events rarely occurring where intravenous selenium was administered at up to 5000 g/day [108, 109]

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A meta-analysis of the initial and replication studies showed a significant association of the homozygous T allele with a 1.5-fold higher risk of developing statin intolerance ( p = 7 10 5 ) (Siddiqui et al., 2017)