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Promotes normal detoxification and liver function
Pai JK, Cahill LE, Hu FB, et al
First identified in human plasma, its concentration declines significantly with agefrom approximately 200 ng/mL in youth to 80 ng/mL by the age of 60 (Pickart and Margolina 2018)
All these findings support the hypothesis that AML cells might benefit from the toleration of higher iron and ROS levels
GSH replenishment in human tissues is difficult due to its shorter half-life, and not easy to penetrate the plasma membrane hence use of prodrugs/precursors such as cysteine, and glycine is the most promising approach 4,45
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