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Because it is a protein, a large amount of ingested glutathione is broken down by the gut and eliminated before reaching the cells

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For those taking multiple doses daily, spacing them evenly throughout the day helps maintain consistent antioxidant levels

28,29 Generally, the metabolic programs that play vital roles in immune cells include glycolysis, the tricarboxylic acid (TCA) cycle, oxidative phosphorylation (OXPHOS), the pentose phosphate pathway (PPP), fatty acid oxidation (FAO), fatty acid synthesis (FAS) and the amino acid metabolic pathway 30 (Fig

10.1186/s12974-022-02515-w J