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Buffer screening of protein formulations using a coarse-grained protocol based on medicinal chemistry interactions

In most epilepsy syndromes the epileptiform discharges are activated during non-rapid eye movements (NREM) sleep (e.g., self-limited epilepsy with centrotemporal spikes, SeLECTS), may occur exclusively during sleep (e.g., electrical status epilepticus during slow-wave sleep, ESES), or after waking from sleep (e.g., juvenile myoclonic epilepsy, West syndrome) are common (4)

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