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Individual variability is significant and depends on starting weight, metabolic factors, medication adherence, dose optimization, lifestyle factors, and genetic variables
Compared with current use (20%) of SGLT2is, widespread use (75%) in the total population with type 2 diabetes was projected to prevent 13,376 non-fatal MIs, 117,240 HF hospitalisations, 6871 ESKD events and 35,989 deaths, but increase the number of non-fatal strokes by 1363 (Table 2)
Citation: Jastreboff, A
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