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Constipation and digestive discomfort Constipation on tirzepatide is the second most common gastrointestinal complaint after nausea
Weight loss plays an important role, but research suggests inflammation reduction may begin through metabolic and hormonal improvements before major weight changes occur
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It is suggested that positive dexamethasone suppression test in a patient without high pre-test probability for Cushing's syndrome be repeated without coadministration of GLP1RA or be supported by additional screening tests for Cushings syndrome
