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Partial evaporation was allowed (until at least 1 ml remained), and water was added to obtain 2 ml samples for liquid chromatography-mass spectrometry (LC-MS) analysis

Across pivotal trials, nausea occurred in 42% of participants on GLP-1 agonists, 45% on dual agonists, and 50% on triple agonists, with similar patterns for vomiting and diarrhea (Table 4 and Figure 2)

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