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There is no evidence that doses above 500mcg produce proportionally better results, and clinical trials using 1mg daily did not dramatically outperform lower doses
[1] [2] Taking more than the prescribed dose can lead to an exaggerated pharmacological response, primarily affecting gastrointestinal function and potentially blood glucose levels
Tirzepatide side effects The most common side effects of tirzepatide are gastrointestinal, particularly during dose escalation
Insulin resistance and endothelial dysfunction: the road map to cardiovascular diseases
J Clin Invest 124: 2456-2463, 2014
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