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All authors critically revised the paper for intellectual content and approved the submitted versions and the final version of the manuscript

After NIR laser irradiation (671 nm), PPa generated ROS to trigger the PEG cleavage, and 98% of ROS-liable DiPt-TK-PEG 2k could be degraded after 30-s irradiation

Unlike prescription GLP-1 receptor agonists, which commonly cause significant nausea, vomiting, and gastrointestinal distress due to delayed gastric emptying, probiotic-related symptoms are typically less severe and mechanistically different

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Proper storage ensures the efficacy and longevity of the supplement.