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Providers may prescribe GLP-1 medications or other FDA-approved weight-management treatments when appropriate

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During the initial OASIS 4 clinical trial, patients on average lost around 17% of their starting weight, though in a later analysis, early responders (people who'd lost more than 10% of their starting weight by week 16) went on to lose 22% on average by the end of 64 weeks

Abstract Leptin, an adipokine related to obesity, is mainly known for its role in regulating energy homeostasis and appetite by working via the leptin receptor

Most patients notice appetite suppression within the first week , with significant weight loss occurring over 3 to 6 months