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5FAD, mice, 5 familial AD, mutations mice
Alimentary pharmacology & therapeutics
Learn more about collagen supplements, including evidence from clinical studies on arthritis and muscle strength and safety
40 To determine whether mutation of G322 alone was sufficient to disrupt PGC development, we generated mice carrying the G322V mutation ( Trim37 G322V/G322V model)
This translocation is supported by Karyopherin 1 (importin 5), that functions as an adaptor molecule, and Karyopherin 1 (importin 1), the transport receptor that allows NRF2 translocation from the cytoplasm to the nuclear side of the NPC, due to Nuclear Localization Signal (NLS) sequences in NRF2 [160]
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