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For histopathological evaluation, skin specimens were collected on Days 7, 14, and 21 using 4-millimeter punch biopsy instruments from different corners of the left-side wound of each rabbit, immediately after planimetry

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We implemented the SQ infusion of OHCbl using a SQ catheter system together with a small, portable pump in four patients with cobalamin-related remethylation disorders in whom frequent IM injections were not or no longer feasible

The stimulus intensity that can be administered in humans is understandably limited, as also it is in animal studies

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