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Research using LPS-stimulated macrophage models and UV-challenged skin cell lines has documented percentage reductions in IL-6 and TNF-alpha secretion following GHK-Cu treatment, with some studies reporting reductions in the 30 to 60% range compared to untreated challenge controls

Inflammatory and hormonal markers are assessed to understand how systemic inflammation, stress response, and hormonal balance may be influencing tissue repair, skin aging, or recovery processes

doi: 10.1098/rsbm.2007.0022 19 ChangSHLimG