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These accumulated metabolites act as competitive inhibitors of nuclear -KG-dependent dioxygenases, including multiple histone demethylases and TET family DNA demethylases and resulting fundamentally alteration the cellular transcriptomic landscape (111,112)
FOXOs: masters of the equilibrium
Matplotlib: A 2D graphics environment
This algae-derived form is the one used in most human clinical research and is considered the gold standard for supplements
Mass spectrometry(MS/MS) assay ESI-MS(LTQ) analysis was performed at the Shanghai Institute for Biological Sciences, Chinese Academy of Science, Shanghai, China
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