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Yes, semaglutide GLP-1, like other GLP-1 receptor agonists, can sometimes lower blood sugar levels too much, leading to a condition known as hypoglycemia
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doi:10.1016/s0083-6729(00)59012-8
However, a peptide can lose its potency due to heat or age without any visible signs
Yen FS, Hou MC, Liu JS, Hsu CC, Hwu CM
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