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Central infusion of GLP-1, but not leptin, produces conditioned taste aversions in rats
Daniel Drucker [Biomarker April 2023] To date, the adverse event profile of GLP-1R agonists is characterized by relatively mild gastrointestinal (GI) side effects, such as nausea, vomiting, and diarrhea
Injectable peptides may cause swelling, pain, or reddening on the injection site
STEP 2 confirmed efficacy in diabetic populations (9.6% weight reduction)
While both UroA and spermidine target cellular maintenance, they affect overlapping as well as distinct signalling pathways
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