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After spinning, supernatant was removed and pellet was resuspended in 0.1 M sodium cacodylate buffer (pH 7,4) + 2.5% glutaraldehyde and stored overnight at 4 C

Effective concentration 0.251 % w/w (optimal ~0.5% w/w) Clinical evidence Studies indicate that ethosomal encapsulation of retinol using TPGS modification substantially reduces degradation rates at room temperature while maintaining particle size stability

Bioscience Reports, May 2021, ePublication 3

This is just one example of how antioxidants work together to protect the body against free-radical induced damage