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it is effective on both pruritus and cholestasis in PFIC, potentially being a disease-modifying intervention

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The topical application of sponge Haliclona sp

Here we showed that the disruption of D2R-DAT interaction by TAT-DAT NT peptide stimulates locomotor behavior in normal and dopamine-depleted Sprague-Dawley rats by increasing extracellular dopamine, suggesting the TAT-DAT NT peptide might also exert beneficial effects in the animal model of ADHD