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That distinction matters because someone microdosing at 2.5 mg long-term is taking a dose the trials only tested for 4 weeks at a time, in service of working up to a higher dose
These anti-inflammatory effects make GHK-Cu relevant not just for acute shoulder injuries but for chronic conditions like tendinopathy where ongoing low-grade inflammation contributes to tissue degeneration
Nat Struct Mol Biol
Some data suggest potential neuroprotective effects of LIRA and SEMA in neurodegenerative diseases,34 through various mechanisms possibly related to improved insulin sensitivity, anti-inflammatory actions, and inhibition of oxidative stress, mediated by GLP-1 receptors also present in astrocytes and microglia
Lilly describes these events as generally mild to moderate with the majority resolving during treatment
