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Due to its antioxidant character, it is widely used in pharmaceutical, cosmetic and food industry
Abdominal pain or discomfort
Jastreboff et al., 2023 (NEJM): estudio fase 2 en adultos con obesidad sin diabetes, reduccin ponderal media de 24.2% a la semana 48 con 12 mg semanales, el mayor efecto reportado para un frmaco incretnico hasta la fecha de publicacin
this dose also provoked the largest percentage of weight loss though the once-weekly injectable dose of semaglutide at 1 mg was similarly effective.35 Cardiovascular Protection In addition to blood glucose and weight loss benefits, GLP-1s have shown effectiveness in improving cardiovascular outcomes and reducing the risk of major cardiovascular events.36 The SELECT trial showed that semaglutide 2.4 mg weekly significantly reduced major adverse cardiovascular events, heart failure-related hospitalizations, cardiovascular deaths, and all-cause mortality in adults with overweight or obesity and established CVD, including those with and without heart failure
Esta funcin es especialmente importante en el hgado, donde el glutatin ayuda a descomponer y eliminar toxinas
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