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Some of the parameters assessed include: Blood tests to measure complete blood count, urea and creatinine levels, liver function, and erythrocyte sedimentation rate Stool tests to determine the presence of blood to confirm melena Endoscopy testing to identify the source of bleeding, such as ulcers or varices Further investigations Individuals with new-onset melena may also undergo gastroscopy (OGD) for additional evaluation

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Observational studies indicate that older GLP-1RA users experience greater proportional lean mass loss than younger adults [14]

[15] Truong TT, Gardner DK