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47 In June 2025, the European Medicines Agency recommended cessation of semaglutide use if a patient is newly diagnosed with NAION
That's how you generate reproducible, publishable data rather than ambiguous results that raise more questions than they answer
Certain preclinical investigations indicate GLP-1 may inhibit inflammatory signaling pathways and reduce oxidative stress in joint tissues
And while most of the current GLP-1 research in addiction focuses on alcohol use disorder, there is also research underway or in progress related to: Nicotine dependence Stimulants (such as cocaine and amphetamines) Opioids (mainly in early and preclinical stages) What Early GLP-1 Addiction Studies Show Clinically What stands out to me clinically is the consistency of the signal emerging around GLP-1 medications and addiction-related cravings
Key takeaways Semaglutide works for ages 12 and up, while phentermine is only approved for people 17 and older
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