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Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially developed for the treatment of type 2 diabetes and obesity, may modulate pathways associated with the hallmarks of aging

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But facial changes are common enough that the American Academy of Dermatology says people taking Wegovy, Ozempic, Zepbound and other GLP-1 medications are likely to notice changes such as loss of facial fullness, sagging skin and a crepey texture

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