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Since IGF-1 can influence glucose utilization, clinicians typically evaluate meal timing, insulin response, and training intensity before determining administration timing

Consequently, while the data reflect reassuring safety, they do not conclusively prove an intrinsic therapeutic benefit for IBD

For example, clinical trials such as LEADER, 11 SELECT, 12 and SURPASS 13 have all shown the cardiovascular benefits of GLP-1 receptor agonists, across virtually all formulations

Adems, estos medicamentos reducen la secrecin de glucagn durante la hiperglucemia, disminuyendo la produccin de glucosa heptica y apoyando an ms el control glucmico

Holst reflects on the advancements in GLP-1 therapy development, particularly the transition to long-acting injectable formulations