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Subjects were asked to fill the questionnaires to subjectively evaluate skin properties at each visit

Research utilizing the Broad Institute's Connectivity Map indicates it influences the expression of over 4,000 genes (~31% of the human genome), shifting gene signatures from a pathological state back to a healthier, regenerative baseline

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Immunostaining for pimonidazole adducts was performed using FITC-conjugated anti-pimonidazole mouse monoclonal antibodies