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[PMID: 16253281] PubMed record related to this compound for laboratory literature review
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The studys most important finding was the average 5.0 kg drop in body weight that was seen with semaglutide, mostly due to a reduction in body fat mass
Two additional enzymes are modified by 4-phosphopantetheine attachment, the cytosolic AASDH (aminoadipate-semialdehyde dehydrogenase) encoded enzyme and the mitochondria-localized DHRS2 encoded enzyme
GLP-1 therapy is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
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