It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)
PLUSSOME VITA C Triple Vitamin C 3-O-Ethyl Ascorbic Acid (stable, brightening) + Ascorbic Acid (direct antioxidant) + Ascorbyl Glucoside (gentle, slow-release) + Ferulic Acid (stabilizer)
Am J Respir Crit Care Med 176(3):270276 Fitzpatrick AM, Teague WG, Burwell L, Brown MS, Brown LA (2011) Glutathione oxidation is associated with airway macrophage functional impairment in children with severe asthma
Evidence from the Clinic Patients who have the best results typically: Adhere to strict sun protection (SPF 50+) Avoid smoking and excessive alcohol Use IVs with oral antioxidants Adhere to a maintenance program Some patients who are not compliant with lifestyle control and only have intermittent infusions, often see little or no transformation
This review summarizes the roles of arginine, tryptophan, glutamine, branched-chain amino acid, serine/glycine/threonine, aspartate/asparagine, and sulfur-containing amino acid metabolism in the dynamic spectrum of macrophage polarization, and further outlines recent advances in systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, type 1 diabetes mellitus, psoriasis, autoimmune hepatitis, and vasculitis
