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Gallbladder problems: Signs of cholelithiasis (gallstones) or cholecystitis (gallbladder inflammation) include abdominal pain, fever, jaundice, and clay-colored stools

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Furthermore, a network meta-analysis examining the effects of GLP-1 RA therapy on body composition reported a greater reduction in lean body mass in the intervention group compared with placebo or active comparators (mean difference = 0.86 kg, 95%CI: 1.30, 0.42)

While it may seem minor compared to other potential side effects, for many patients, this can be a source of discomfort and embarrassment, affecting their quality of life

Oncology (Huntingt.) 14 , 1116 (2000)