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Direct contact with the coldest surfaces can cause localized freezing, which is just as damaging as heat exposure
And even though many expert voices and even major task forces have called for the inclusion of pregnant women in clinical trials over the last several decades, she added, the lack of inclusion persists
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This in turn disrupts the BBB, recruits peripheral immune cells, and induces further ferroptosis, creating a vicious cycle of ferroptosisinflammationferroptosis. Whether this process functions as an inflammation amplifier in specific brain regions, and whether ferroptosis inhibition alone can mitigate inflammation or must be combined with anti-inflammatory therapies, remains unclear
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