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Description

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The compound's high-affinity receptor binding and robust downstream pathway activation make it suitable for mechanistic studies examining IRS-1/PI3K/AKT/mTOR signalling cascade components

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Like other cancer types, c-MYC is highly expressed in endometrial tumors (Kim et al., 2013) and immunohistochemical localization studies revealed a 78.3% positive rate of c-MYC in endometrial cancer tissues with amplified c - MYC in 25% of the cases (Zhang et al., 2018

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