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Another recently completed study is with the ns-MRA, balcinrenone, which was investigated in combination with the SGLT2i dapagliflozin (phase 2b MIRACLE [NCT04595370] study) (Table 3)
This tier has the highest rate of independent testing failures in community reports including product that tests as sterile water with no benzyl alcohol, sub-spec preservative concentrations, and endotoxin levels above USP limits
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This extended window provides a safety buffer beyond the pharmacokinetic clearance timeline
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