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Weight loss and improvement of insulin resistance and circulating insulin levels are considered essential for the clinical management of hyperandrogenic women with PCOS and obesity, as this may contribute to attenuating androgen excess and improve ovarian function 5,14,15,16

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Melanotan II also influences other melanocortin receptors, which may result in increased libido and appetite suppression

But obesity can cause many diseases

GLP-1 research spans a remarkably broad range of biological systems owing to the widespread distribution of the GLP-1 receptor across multiple tissue types