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SLC7A11 deficiency accelerates the progression of high-fat diet-induced MASLD through ferroptosis induced by classical cystine/cysteine deficiency, while serine deficiency and consequent obstruction of de novo synthesis of cysteine are responsible for the progression of ferroptosis induced MAFLD in hepatic SLC7A11 overexpressing mice

GHK-Cu spray is used by laboratories studying copper-peptide signaling in skin remodeling, hair follicle biology, and antioxidant pathways

Two points deserve emphasis

Samples were snap-frozen in liquid nitrogen and stored at 80 C until further analysis

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