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Any patient presenting with flank pain, hematuria, or other concerning urinary symptoms should be promptly evaluated, typically with non-contrast CT or renal ultrasound

This prolonged, supraphysiological stimulation results in greater glucose-lowering effects, more pronounced appetite suppression, and clinically significant weight loss that varies by medication and dose: approximately 5-8% with liraglutide 3 mg, 10-15% with semaglutide 2.4 mg, and 15-22% with tirzepatide at higher doses

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