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Because of this dual mechanism, many patients begin tirzepatide at lower starting doses than they might with semaglutide, even though tirzepatide's clinical efficacy tends to be more pronounced

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Enucleation and clearance of organelles are crucial events of erythropoiesis, which occur at the stage of erythroblasts and/or reticulocytes

Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for two distinct indications: treatment of type 2 diabetes mellitus (Mounjaro) and chronic weight management (Zepbound)