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This inflammatory response worsens neuronal damage, raises seizure frequency and severity, and creates a vicious cycle that further impairs neuronal function, contributing to the chronic nature of the disorder ( 2.2 The key impact of oxidative stress in neuronal damage during epilepsy Owing to the key roles of neuroinflammation and oxidative stress in epilepsy, targeting these pathways presents a promising therapeutic approach

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Regulatory Status GLP-3 (Reta) (LY3437943) is an investigational compound developed by Eli Lilly