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Studies using GCS inhibitors in multiple different animal models of PKD have demonstrated that reducing the production of GSLs can slow cyst growth and preserve kidney function
H., Hermodson, M
(2002) in the Journal of Clinical Endocrinology and Metabolism
Besides berberine, other botanicals including citrus fruit extracts, green tea, saffron, and coffee bean extract have been studied for their potential role in GLP-1 production with mixed results
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