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Changes in the local microenvironment within metabolic organs have a significant impact on the function of tissue-resident and newly recruited macrophages, leading to metabolic inflammation linked to obesity (Wculek et al., 2022)

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Early studies suggest retatrutide may cause more weight loss than semaglutide and tirzepatide, with some people losing 30% of their body weight or more

doi: 10.3390/nu11112579 64 ChenSWeiWChenMQinXQiuLZhangLet al