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Notable findings include: In the SURMOUNT-1 trial of tirzepatide for the treatment of obesity, secondary findings showed improvements in the GLP-1 treatment group in systolic blood pressure (-7.2mm Hg), diastolic blood pressure (-4.8mm Hg), triglycerides (-24.8mg/dl), fasting insulin (-42.9mIU liter), and total cholesterol (-4.8mg/dl)

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These medications work by mimicking the action of the naturally occurring GLP-1 hormone, which is released from the intestine in response to food intake

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Chronic inflammation, oxidative stress, and metabolic dysfunction often contribute to these conditions

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The weight loss period is the window for habit formation, not a replacement for it

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Sodium-glucose cotransporter-2 inhibitors and subtype-specific dementia risk: a multinational and multiethnic cohort study

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